Authors
Fauziyya Muhammad, Kenneth A Weber, Sandrine Bédard, Grace Haynes, Lonnie Smith, Ali F Khan, Sanaa Hameed, Kathyrn Gray, Kathleen McGovern, Michael Rohan, Lei Ding, Michael Van Hal, Douglas Dickson, Mazin Al Tamimi, Todd Parrish, Yasin Dhaher, Zachary A Smith
Publication date
2024/11/1
Journal
The Spine Journal
Volume
24
Issue
11
Pages
2045-2057
Publisher
Elsevier
Description
BACKGROUND CONTEXT
Degenerative cervical myelopathy (DCM) is characterized by spinal cord atrophy. Accurate estimation of spinal cord atrophy is key to the understanding of neurological diseases, including DCM. However, its clinical application is hampered by difficulties in its precise and consistent estimation due to significant variability in spinal cord morphometry along the cervical spine, both within and between individuals.
PURPOSE
To characterize morphometrics of the compressed spinal cord in DCM patients. We employed our semiautomated analysis framework that incorporates the Spinal Cord Toolbox (SCT) and a normalization approach to effectively address the challenges posed by cord compression in these patients. Additionally, we examined the clinical relevance of these morphometric measures to enhance our understanding of DCM pathophysiology.
STUDY DESIGN
Prospective study …
Total citations
20251
Scholar articles
F Muhammad, KA Weber, S Bédard, G Haynes, L Smith… - The Spine Journal, 2024